Oct 18, 2026
Niclosamide is a decades-old anti-parasitic drug now being studied for cancer, but the evidence is still mostly from cell and animal studies. It disrupts several pathways tumors rely on (STAT3, Wnt, mTOR, mitochondrial energy). Its main obstacle is poor absorption into the bloodstream, so many papers test new formulations and modified molecules.
Three cancer trials are currently active on ClinicalTrials.gov; all are small, early-phase studies.
NCT05188170
NCT02807805
NCT07683013
Sources
PubMed search: niclosamide AND cancer
ClinicalTrials.gov search: niclosamide in cancer conditions